mitochondria

Daily

Cornerstone’s cancer metabolism drugs sap tumor cells’ energy to replicate

Monoclonal antibodies? So passé. Cancer metabolism drugs are emerging as the therapeutic to watch, or so says Cornerstone Pharmaceuticals CEO Steve Carchedi. Cornerstone’s approach is to develop anticancer drugs that target mitochondrial metabolism – in essence cutting off the energy supply that allows cancer cells to grow and develop. Its lead candidate, CPI-613, inhibits two enzymes that are […]

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Fat-based Parkinson’s drug headed to clinical trial with $6.5M in angel money

There’s a generalized consensus that “good” fats – like Omega-3 fatty acids – could help improve mental acuity, even combat neurodegenerative disease. Bay Area startup Retrotope is riffing off this idea, engineering what could be a super-good fat that treats aging-related conditions like Alzheimer’s, Parkinson’s and diabetic retinopathy. It just received $6.5 million in angel funding to bring its fatty drug to the […]